Abstract
IN the course of work on the serum colloidal gold reaction1,2 it was noted that the thymol which was at first used to inhibit the growth of moulds in the barbitone buffer (pH. 7·8) produced a marked turbidity or precipitate with certain sera. These sera were usually from patients with parenchymatous liver disease and also gave positive colloidal gold reactions, and it soon became evident that there was a close correlation between the thymol turbidity and the gold test.
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References
Maclagan, N. F., Brit. J. Exp. Path., 25, 15 (1944).
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MACLAGAN, N. Thymol Turbidity Test: a New Indicator of Liver Dysfunction. Nature 154, 670–671 (1944). https://doi.org/10.1038/154670a0
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DOI: https://doi.org/10.1038/154670a0
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