Abstract
VARIOUS opinions have been expressed on the nature of the cells lining the venous sinusoids of the spleen1. They have been described as forming a type of internal epithelium, as muscle cells and as separated, longitudinal endothelial ridges. Klemperer accepted Mollier's evidence2 that the wall of a splenic sinus is formed by a cytoplasmic reticulum with reinforcing fibres, essentially identical to the general cytoplasmic and fibrillar reticulum of the pulp. As recently as 1957 Weiss3 stated that splenic cords are collapsed splenic sinuses, and the preponderant cell type in the cords is the same as that lining sinuses.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Klemperer, P., Handbook of Hematology, edit. by Downey, H., 3, 1587 (Hoeber, New York, 1938).
Mollier, Arch. mikr. Anat., 76, 608 (1910–11) (quoted by Klemperer).
Weiss, L., Ann. N.Y. Acad. Sci., 73, 131 (1958).
Braunstein, H., Freiman, D. G., and Gall, E. A., Cancer, 11, 829 (1958).
Pearse, A. G. E., Histochemistry: Theoretical and Applied, second edit., 868 (Churchill, London, 1960).
Marshall, A. H. E., An Outline of the Cytology and Pathology of the Reticular Tissue, 23, 28 (Oliver and Boyd, Edinburgh, 1956).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DORFMAN, R. Nature of the Sinus Lining Cells of the Spleen. Nature 190, 1021–1022 (1961). https://doi.org/10.1038/1901021a0
Issue Date:
DOI: https://doi.org/10.1038/1901021a0
This article is cited by
-
Deposition of lipopigment — a new feature of human splenic sinus endothelium (SSE)
Virchows Archiv A Pathological Anatomy and Histopathology (1990)
-
Esteraseaktivität, Proteingehalt und Gewicht der Milz röntgenganzkörperbestrahlter Ratten unter Berücksichtigung funktionsmorphologischer Gesichtspunkte
Virchows Archiv B Cell Pathology (1969)
-
Nature of human spleen red pulp cells with special reference to sinus lining cells
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie (1968)
-
Histochemische Reaktion und ?negative staining? von Zellfraktionen
Histochemie (1967)
-
Zur Cytologie und Fermenteytochemie der menschlichen Milz
Klinische Wochenschrift (1967)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
