Abstract
INVESTIGATIONS by several authors1,2 have demonstrated that paramagnetic metal ions produce a certain amount of resistance to radiation in cells. This fact is due partly to the redox effect of these ions3, and partly to the facilitation of forbidden transitions of excited electron states4. Since different nucleic acids contain trace elements in significant amounts5, and since the biological activity of nucleic acids is dependent to a large extent on their trace-element content6–8, it seemed essential to us to investigate the trace-element content of those most important macro-molecules of the cell before and after irradiation. It was also shown that by roentgen irradiation removal of Ca++ and Mg++ from nucleohistone is possible, whereby at the same time reduction in DNA occurs9.
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ALTMANN, H., STEHLIK, G. & KAINDL, K. In vivo Investigation of the Removal of Trace Elements from Nucleic Acids of Yeast by Ionizing Radiation. Nature 199, 823 (1963). https://doi.org/10.1038/199823a0
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DOI: https://doi.org/10.1038/199823a0
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