Abstract
THE production of a simple derivative of lysergic acid in submerged culture by a strain of Claviceps paspali was reported by Arcamone et al.1 and identified as D-lysergic acid α-hydroxyethylamide. The behaviour of the strain during in vivo development on a host plant has been examined to establish whether this fungus produces the same lysergic acid derivative as in submerged culture.
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References
Arcamone, F., Chain, E. B., Ferretti, A., Minghetti, A., Penella, P., Tonolo, A., and Vero, L., Proc. Roy. Soc., B, 155, 26 (1961).
Wells, D. A., and Soffe, R., J. Agric. Eng. Res., 7, 42 (1962).
Kobel, H., Brunner, R., and Brack, A., Experientia, 18, 140 (1962).
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BIANCHI, P., CHAIN, E., MANTLE, P. et al. Formation of a Lysergic Acid Derivative during the Parasitic Development of a Strain of Claviceps paspali Stevens and Hall. Nature 202, 312–313 (1964). https://doi.org/10.1038/202312a0
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DOI: https://doi.org/10.1038/202312a0
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