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Crossover Model of Antibody Variability

Abstract

Several unsatisfactory models have been proposed to account for the variation in the primary structure of the polypeptide chains in the antibody molecule. A new model is proposed here; it is based on intrachromosomal crossing over during the development of plasma cells.

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WHITEHOUSE, H. Crossover Model of Antibody Variability. Nature 215, 371–374 (1967). https://doi.org/10.1038/215371a0

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