The types of chemical signal that a neuron synthesizes and communicates with were thought to be genetically encoded and largely invariable. It seems, though, that if a neuron's activity changes, so too do its signals.
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Goulding, M. A matter of balance. Nature 429, 515–517 (2004). https://doi.org/10.1038/429515a
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DOI: https://doi.org/10.1038/429515a
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