“Do not speak — unless it improves on silence” is generally wise advice, and is even vital for a subset of essential genes. New studies describe how, when appropriate, the silence of these genes is broken.
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Jones, R. Reversing the 'irreversible'. Nature 450, 357–359 (2007). https://doi.org/10.1038/450357a
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DOI: https://doi.org/10.1038/450357a