A hallmark of Alzheimer's disease is the presence in the brain of protein deposits, or plaques, which are thought to form over a long period. But studies in mice suggest that the plaques can grow overnight.
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Masliah, E. Alzheimer's in real time. Nature 451, 638–639 (2008). https://doi.org/10.1038/451638a
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DOI: https://doi.org/10.1038/451638a