Obesity is a major health problem in developed countries and a growing one in the developing world. It increases the risk of diabetes, heart disease, fatty liver and some forms of cancer. A better understanding of the biological basis of obesity should aid its prevention and treatment.
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Friedman, J. M. Modern science versus the stigma of obesity. Nature Med. 10, 563–569 (2004).
Eckel, R. H. Clinical practice. Nonsurgical management of obesity in adults. N. Engl. J. Med. 358, 1941–1950 (2008).
Coll, A. P., Farooqi, I. S. & O'Rahilly, S. The hormonal control of food intake. Cell 129, 251–262 (2007).
Speakman, J. R. A nonadaptive scenario explaining the genetic predisposition to obesity: the 'predation release' hypothesis. Cell Metab. 6, 5–12 (2007).
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Friedman, J. M. A war on obesity, not the obese. Science 299, 856–858 (2003).
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Jeffery M. Friedman consults for Amylin Pharmaceuticals. He also has a financial interest in leptin through the Rockefeller University patent policy.
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Friedman, J. Causes and control of excess body fat. Nature 459, 340–342 (2009). https://doi.org/10.1038/459340a
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DOI: https://doi.org/10.1038/459340a
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