DNA is the material of choice for making custom-designed, nanoscale shapes and patterns through self-assembly. A new technique revisits old ideas to enable the rapid prototyping of more than 100 such DNA shapes. See Letter p.623
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References
Wei, B., Dai, M. & Yin, P. Nature 485, 623–626 (2012).
Seeman, N. C. J. Theor. Biol. 99, 237–247 (1982).
Chen, J. & Seeman, N. C. Nature 350, 631–633 (1991).
Rothemund, P. W. K. Nature 440, 297–302 (2006).
Andersen, E. S. et al. Nature 459, 73–76 (2009).
Douglas, S. M. et al. Nature 459, 414–418 (2009).
Dietz, H., Douglas, S. M. & Shih, W. M. Science 325, 725–730 (2009).
Han, D. et al. Science 332, 342–346 (2011).
Maune, H. T. et al. Nature Nanotechnol. 5, 61–66 (2010).
Endo, M., Katsuda, Y., Hidaka., K. & Sugiyama, H. Angew. Chem. Int. Edn 49, 9412–9416 (2010).
Douglas, S. M. et al. Science 335, 831–834 (2012).
Winfree, E., Liu, F., Wenzler, L. A. & Seeman, N. C. Nature 394, 539–544 (1998).
Rothemund, P. W. K. & Winfree, E. Proc. 32nd Annu. Symp. Theor. Comput. 459–468 (2000).
Andersen, E. S. et al. ACS Nano 2, 1213–1218 (2008).
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P.W.K.R. is the inventor on a patent that describes the method of ‘scaffolded DNA origami’. For certain nanopatterning applications, the method in the paper described by Yin et al. is a competitor with the method of DNA origami.
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Rothemund, P., Andersen, E. The importance of being modular. Nature 485, 584–585 (2012). https://doi.org/10.1038/485584a
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DOI: https://doi.org/10.1038/485584a
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