Killing off cells that refuse to die on their own has proved a powerful anti-ageing strategy in mice. Now it's about to be tested in humans.
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25 October 2017
Reference 4 in this story originally omitted the journal name. This has now been added.
References
Baker, D. J. et al. Nature Cell Biol. 10, 825–836 (2008).
Baker, D. J. et al. Nature 479, 232–236 (2011).
Baar, M. P. et al. Cell 169, 132–147 (2017).
Schafer, M. J. et al. Nature Commun. 8, 14532 (2017).
Jeon, O. H. et al. Nature Med. 23, 775–781 (2017).
Baker, D. J. et al. Nature 530, 184–189 (2016).
Coppé, J.-P. et al. PLoS Biol. 6, e301 (2008).
Kuilman, T. et al. Cell 133, 1019–1031 (2008).
Acosta, J. C. et al. Cell 133, 1006–1018 (2008).
Demaria, M. et al. Cancer Discov. 7, 165–176 (2017).
Biran, A. et al. Aging Cell 16, 661–671 (2017).
Zhu, Y. et al. Aging Cell 14, 644–658 (2015).
Fuhrmann-Stroissnigg, H. et al. Nature Commun. 8, 422 (2017).
Kirkland, J. L. & Tchkonia, T. EBioMedicine 21, 21–28 (2017)
Chang, J. et al. Nature Med. 22, 78–83 (2016).
Zhu, Y. et al. Aging Cell 15, 428–435 (2016).
Yosef, R. et al. Nature Commun. 7, 11190 (2016).
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Megan Scudellari is a science journalist based in Boston, Massachusetts.
- Megan Scudellari
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Scudellari, M. To stay young, kill zombie cells. Nature 550, 448–450 (2017). https://doi.org/10.1038/550448a
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DOI: https://doi.org/10.1038/550448a