Abstract
High levels of IL-6 were found in 50% of 114 patients with primary ovarian cancer. IL-6 sensitivity was lower than that of CA 125, and the combination of both assays did not increase the sensitivity of CA 125 alone. However, elevated IL-6 serum levels were correlated with a poor prognosis since patients with low IL-6 levels had a better survival than patients with high IL-6 levels (P = 0.0009). Multivariate analysis revealed that IL-6 positivity has an independent value.
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Scambia, G., Testa, U., Benedetti Panici, P. et al. Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer. Br J Cancer 71, 354–356 (1995). https://doi.org/10.1038/bjc.1995.71
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DOI: https://doi.org/10.1038/bjc.1995.71