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Cell wall mannan of Candida krusei mediates dendritic cell apoptosis and orchestrates Th17 polarization via TLR-2/MyD88-dependent pathway
Scientific Reports Open Access 20 November 2018
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References
Goodman JL, Winston DJ, Greenfield RA, Chandrasehar PH, Fox B, Kaizer H et al. A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation. N Engl J Med 1992; 326: 845–851.
van Burik JAH, Ratanatharathorn V, Stepan DE, Miller CB, Lipton JH, Vesole DH et al. Micafungin versus fluconazole for prophylaxis against invasive fungal infections during neutropenia in patients undergoing hematopoietic stem cell transplantation. Clin Infect Dis 2004; 39: 1407–1416.
Pfaller MA, Messer MA, Moet GJ, Jones RN, Castanheira M . Candida bloodstream infections: comparison of species distribution and resistance to echinocandin and azole antifungal agents in intensive care unit (ICU) and non-ICU settings in the SENTRY antimicrobial surveillance program (2008-2009). Int J Antimicrob Agents 2011; 38: 65–69.
Hakki M, Staab JF, Marr KA . Emergence of a Candida krusei isolate with reduced susceptibility to caspofungin during therapy. Antimicrob Agents Chemother 2006; 50: 2522–2524.
Park S, Kelly R, Kahn JN, Robles J, Hsu MJ, Register E et al. Specific substitutions in the echinocandin target FKS1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates. Antimicrob Agents Chemother 2005; 49: 3264–3273.
EUCAST.. EUCAST definitive document EDef 7.1: method for the determination of broth dilution MICs of antifungal agents for fermentative yeasts. Clin Microbiol Infect 2008; 14: 398–405.
Desnos-Ollivier M, Bretagne S, Raoux D, Hoinard D, Dromer F, Dannaoui E . Mutations in the fks1 gene in Candida albicans C. tropicalis, and C. krusei correlate with elevated caspofungin MICs uncovered in AM3 medium using the method of the European Committee on Antibiotic Susceptibility Testing. Antimicrob Agents Chemother 2008; 52: 3092–3098.
Jacobsen MD, Gow NA, Maiden MC, Shaw DJ, Odds FC . Strain typing and determination of population structure of Candida krusei by multilocus sequence typing. J Clin Microbiol 2007; 45: 317–323.
Pfaller MA, Diekema DJ, Andes D, Arendrup MC, Brown SD, Lockhart SR et al. Clinical breakpoints for the echinocandins and Candida revisited: integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria. Drug Resist Updat 2011; 14: 164–176.
Shah DN, Yau R, Lasco TM, Weston J, Salazar M, Palmer HR et al. Impact of prior inappropriate fluconazole dosing on isolation of fluconazole-nonsusceptible Candida species in hospitalized patients with candidemia. Antimicrob Agents Chemother 2012; 56: 3239–3243.
Acknowledgements
We thank Catherine Blanc and Damien Hoinard for technical assistance. We thank the Platform Genotyping of Pathogen and Public Health, Institut Pasteur, for sequencing facility.
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Tavernier, E., Desnos-Ollivier, M., Honeyman, F. et al. Development of echinocandin resistance in Candida krusei isolates following exposure to micafungin and caspofungin in a BM transplant unit. Bone Marrow Transplant 50, 158–160 (2015). https://doi.org/10.1038/bmt.2014.230
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DOI: https://doi.org/10.1038/bmt.2014.230
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