Regulatory T cells (Tregs) are crucial in maintenance of immune homeostasis. In 2013, three studies found that microbiota-derived short-chain fatty acids promote the expansion and differentiation of Tregs, revealing a form of chemical-mediated communication between the commensal microbiota and the immune system that affects immune mechanisms.
- MILESTONES
Microbially-produced short-chain fatty acids induce regulatory T cell production
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