Abstract
Fifty-five children with pure anisometropic amblyopia presented consecutively between 1983 and 1986. Analysis of their records was undertaken with respect to the age at presentation, the initial visual acuity after spectacle correction, and the final acuity attained after treatment. The results show that the final vision achieved does not depend on the age at presentation. The implications of these findings are discussed and their relations to the sensitive period for the development of amblyopia from other causes outlined.
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von Noorden GK : Classification of amblyopia. Am J Ophthalmol 1967, 63: 238–44.
Boothe RG, Dobson V, Teller DY : Postnatal development of vision in human and non-human primates. Ann Rev Neurosci. 1985, 8: 495–545.
Hubel DH and Wiesel DN : The period of susceptibility to physiological effects of unilateral eye closure in kittens. J Physiol 1970, 206: 419–36.
von Noorden GK : New clinical aspects of stimulus deprivation amblyopia. Am J Ophthalmol 1981, 92: 416–21.
Awaya S, Sugawara M, Myake S, Isomura Y : Form vision deprivation amblyopia and the results of its treatment—with specific reference to the critical period. Jpn J Ophthalmol 1980, 24: 241–50.
Willshaw HE : Traditional clinical methods of visual assessment in childhood. Trans Ophthalmol Soc UK 1985, 104: 641–5.
Phelps WL and Muir V : Anisometropia and strabismus. Am Orthopt J 1977, 27; 131–3.
Ingram RM : Refraction as a basis for screening children for squint and amblyopia. Br J Ophthalmol 1977, 61: 8–15.
Katsumi O, Tanino T, Hirose T : Effect of aniseikonia on binocular function. Invest Ophthalmol Vis Sci 1986, 27: 601–4.
Johnstone WW and Maclaren DS : Refraction anomalies in Tanganyikan children. Br J Ophthalmol 1963, 47: 95–108.
Helveston EM and von Noorden GK : Microtropia: a newly defined entity. Arch Ophthalmol 1967, 78: 272–81.
Simons K and Reinecke RD . A reconsideration of amblyopia screening and stereopsis. Am J Ophthalmol 1974, 78: 707–13.
Sen DK . Results of treatment of anisohypermetropic amblyopia without strabismus. Br J Ophthalmol 1982, 66: 680–4.
de Vries J . Anisometropia in children: analysis of a hospital population. Br J Ophthalmol 1985, 69: 504–7.
Kivlin JD and Flynn JT . Therapy of anisometropic amblyopia. J Paed Ophthalmol Strabismus 1981, 18: 47–56.
Vereecken EP and Brabant P . Prognosis for vision in amblyopia after loss of good eye. Arch Ophthalmol 1984, 102: 220–4.
von Noorden GK and Crawford MLJ . The sensitive period. Trans Ophthal Soc UK 1979, 99: 442–6.
Hubel DH and Wiesel TN . Period of susceptibility to physiological effects of unilateral eye closure in kittens. J Physiol 1970, 206: 419.
Harwerth RS, Smith EL, Duncan GC, Crawford MLJ, von Noorden GK . Multiple sensitive periods in the development of the primate visual system. Science 1982, 232: 235–7.
Vaegan and Taylor D . Critical period for deprivation amblyopia in children. Trans Ophthalmol Soc UK 1979, 99: 432–9.
Teller DY . The development of visual acuity in human and monkey infants. Trends Neurosci. 1981, 4: 21–4.
Smith EL, Harweth RS, Crawford MLJ . Optically induced anisometropia in monkeys: Behavioural studies. Invest Ophthalmol Vis Sci (Suppl) 1983, 24: 22–4.
Ikeda H and Tremain KE : Amblyopia resulting from penalisation: neurophysiological studies of kittens reared with atropinisation of one or both eyes. Br J Ophthalmol 1978. 62: 21–8.
Deering KR and Peck CK . Amblyopia results from chronic blurring of visual images during development. Develop Brain Res 1984, 15: 302–6.
von Noorden GK : Amblyopia caused by unilateral atropinisation. Ophthalmology 1981, 88: 131–3.
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Hardman Lea, S., Loades, J. & Rubinstein, M. The sensitive period for anisometropic amblyopia. Eye 3, 783–790 (1989). https://doi.org/10.1038/eye.1989.122
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DOI: https://doi.org/10.1038/eye.1989.122
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