Abstract
The City Eye Study is a nine year longitudinal prospective epidemiological study. During the first three year phase the study recruited 1029 volunteers, aged between 54 and 65 years, primarily from companies and organisations working in or around the City of London.
The analysis of the first cohort data shows a significant association between nuclear lens opacities and moderate to heavy cigarette smoking. The Relative Risk for nuclear lens opacity and cigarette smoking ranges from 1.0 for past light-smokers through 2.6 for past heavy-smokers, to 2.9 for present heavy smokers.
Similar content being viewed by others
Article PDF
References
West S, Taylor H, Newland H : Evaluation of Photographic Method for Grading Lens Opacities for Epidemiological Research. ARVO 1986, 27: 2: 44.
Hollows F and Graham P : Intra-ocular pressure, glaucoma and glaucoma suspects in a defined population. Br J Ophthalmol 1966, 50: 570–86.
Human cataract formation. CIB A Foundation Symposium 106 1984. Nugent J, Whelan J (eds) Pitman, London.
Ansari NH, Awasthi YC, Strivastava SK : Role of glycosylation in protein disulphide formation and cataractogenesis. Exp Eye Res 1980, 31: 9–19.
Brokman R : Cataracts and photochemical damage in the lens. CIBA Foundation Symposium 106 1984, 88-109. Nugent J, Whelan J (eds) Pitman, London.
Ederer F in Blindness (1977-78). American Association of workers for the blind inc. Annual. Washington DC.
Cullinan T . The epidemiology of visual disability. Health Services Research Unit 1977; report no.28. University of Kent, Canterbury.
Gibson JM, Rosenthal A, Lavery J : A study of the prevalence of eye disease in the elderly in an English community. Trans Ophthalmol Soc UK 1984, 104: 196–203.
Sommer A : Cataracts as an epidemiologic problem. Am J Ophthalmol 1977, 83: 334–40.
Clayton R, Cuthbert J, Duffy J, Seth J, Phillips C, Bartholomew R, Reid J : Epidemiological and other studies in the assessment of factors contributing to cataractogenesis. CIBA Foundation Symposium 1984, 106: 25–47.
Hockwin O and Koch H : Combined noxious influences In: Cataract and the abnormalities of the Lens (Bellows J, ed) Grune and Stratton, New York, 1975, 243–5.
Hesse R : Anterior lens opacities in prolonged phenothiazine therapy. Ann Ophthalmol 1979, 11: 1212.
Salka H and Prchal J : Effect of corticosteroids on cataract formation. Arch Ophthalmol 1980, 98: 1773.
Minassian DC, Mehra V, Jones BR : Dehydrational crises from severe diarrhoea or heat stroke and risk of cataract. Lancet 1984, i: 751–3.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Flaye, D., Sullivan, K., Cullinan, T. et al. Cataracts and cigarette smoking: The City Eye Study. Eye 3, 379–384 (1989). https://doi.org/10.1038/eye.1989.56
Issue Date:
DOI: https://doi.org/10.1038/eye.1989.56
This article is cited by
-
Smoking complicates the course of non-infectious uveitis
Graefe's Archive for Clinical and Experimental Ophthalmology (2011)
-
External factors in the development of cataract
Eye (2005)
-
Antioxidant systems in rat lens as a function of age: Effect of chronic administration of vitamin E and ascorbate
Aging Clinical and Experimental Research (1999)
-
Polarising light biomicroscopy and the relation between visual acuity and cataract
Eye (1995)
-
Antioxidative Vitamine und Katarakte im Alter
Zeitschrift für Ernährungswissenschaft (1995)