Abstract
We describe a patient who presented with a rapidly growing neoplasm of the lacrimal gland which histologically was a sebaceous gland carcinoma. The eyelid was entirely normal on examination under anaesthesia. Sebaceous differentiation has been described on only three previous occasions, arising within pre-existing tumours of the lacrimal gland such as pleomorphic adenoma. In this case there is a single tumour cell line within normal lacrimal gland, and the eyelid is normal. This points to a previously unreported diagnosis of primary sebaceous carcinoma of the lacrimal gland.
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Font RL . Eyelids and lacrimal drainage system. In: Spencer WH, editor. Ophthalmic pathology: an atlas and textbook, vol 3, 3rd ed. Philadelphia: WB Saunders, 1986:2200–14.
Ansai 2, Hashimoto H, Aoki T, Hozumi Y, Aso K . A histo-chemical and immunohistochemical study of extra-ocular sebaceous carcinoma. Histopathology 1993;22:127–33.
Ginsberg J . Present state of meibomian gland carcinoma. Arch Ophthalmol 1965;73:271–7.
Shields J, Font RL . Meibomian gland carcinoma presenting as a lacrimal tumour. Arch Ophthalmol 1974;92:304–6.
Font RL, Gamel JW . Epithelial tumours of the lacrimal gland: an analysis of 265 cases. In: Jakobiec FA, editor. Ocular and adnexal tumours. Birmingham: Aesculapis Publishing, 1978:787–805.
Konrad EA, Thiel HJ . Adenocarcinoma of the lacrimal gland with sebaceous differentiation: a clinical study using light and electron microscopy. Graefes Arch Clin Exp Ophthalmol 1983;221:81–5.
Witschel H, Zimmerman LE . Malignant mixed tumour of the lacrimal gland: a clinicopathologic report of two unusual cases. Graefes Arch Clin Exp Ophthalmol 1981;216:327–37.
Font RL . Orbit. In: Spencer WH, editor. Ophthalmic Pathology: an atlas and textbook, vol. 3, 3rd ed. Philadelphia: WB Saunders, 1986:2489–93.
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Harvey, P., Parsons, M. & Rennie, I. Primary sebaceous carcinoma of lacrimal gland: A previously unreported primary neoplasm. Eye 8, 592–595 (1994). https://doi.org/10.1038/eye.1994.143
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DOI: https://doi.org/10.1038/eye.1994.143
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