Sir,
The opinions expressed by Mr David Spalton1 are absolutely correct.
There is apparent fusion of the anterior and posterior capsules, as stated. 5-Fluorouracil may well only delay the onset of PCO, however clinical trials need to be carried out to determine its long-term effectiveness in preventing PCO. Sealed irrigation of the capsular bag, under positive pressure to inflate the bag fully, using Perfect Capsule, should enable an irrigating solution to reach the equatorial cells, eliminating them and so hopefully ensuring a clear and supple capsule.
References
Spalton DJ . Re: The report ‘irrigation of the capsular bag using a sealed-capsule irrigation device and 5-fluorouracil’ by Milverton. Eye Advance online publication, 19 February 2010; doi:10.1038/eye.2010.13.
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Milverton, E. Reply to Mr Spalton. Eye 24, 1299 (2010). https://doi.org/10.1038/eye.2010.15
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DOI: https://doi.org/10.1038/eye.2010.15