Several genes were duplicated during human evolution. It seems that one such duplication gave rise to a gene that may have helped to make human brains bigger and more adaptable than those of our ancestors.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Possible roles of deep cortical neurons and oligodendrocytes in the neural basis of human sociality
Anatomical Science International Open Access 27 November 2023
-
mmquant: how to count multi-mapping reads?
BMC Bioinformatics Open Access 15 September 2017
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Konopka, G. et al. Nature 462, 213–217 (2009).
Enard, W. et al. Cell 137, 961–971 (2009).
Dennis, M. Y. et al. Cell 149, 912–922 (2012).
Charrier, C. et al. Cell 149, 923–935 (2012).
Guerrier, S. et al. Cell 138, 990–1004 (2009).
Sudmant, P. H. et al. Science 330, 641–646 (2010).
Elston, G. N., Benavides-Piccione, R. & DeFelipe, J. J. Neurosci. 21, RC163 (2001).
Benavides-Piccione, R., Ballesteros-Yanez, I., DeFelipe, J. & Yuste, R. J. Neurocytol. 31, 337–346 (2002).
Preuss, T. M., Cáceres, M., Oldham, M. C. & Geschwind, D. H. Nature Rev. Genet. 5, 850–860 (2004).
Petanjek, Z. et al. Proc. Natl Acad. Sci. USA 108, 13281–13286 (2011).
Somel, M. et al. Proc. Natl Acad. Sci. USA 106, 5743–5748 (2009).
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
About this article
Cite this article
Geschwind, D., Konopka, G. Genes and human brain evolution. Nature 486, 481–482 (2012). https://doi.org/10.1038/nature11380
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature11380
This article is cited by
-
Possible roles of deep cortical neurons and oligodendrocytes in the neural basis of human sociality
Anatomical Science International (2024)
-
mmquant: how to count multi-mapping reads?
BMC Bioinformatics (2017)
-
Cognitive Functions: Human vs. Animal – 4:1 Advantage |-FAM72–SRGAP2-|
Journal of Molecular Neuroscience (2017)