The first crystal structures of class B G-protein-coupled receptors have been solved. They reveal features that might inform drug-development strategies for diseases ranging from osteoporosis to diabetes. See Articles p.438 & p.444
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Sexton, P., Wootten, D. Meet the B family. Nature 499, 417–418 (2013). https://doi.org/10.1038/nature12413
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DOI: https://doi.org/10.1038/nature12413