Information about taste sensations, such as bitter or sweet, is relayed from the mouse tongue to the brain through taste-specific pathways. It emerges that semaphorin proteins guide the wiring of these pathways. See Letter p.330
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Li, J., Luo, L. A bitter–sweet symphony. Nature 548, 285–287 (2017). https://doi.org/10.1038/nature23537
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DOI: https://doi.org/10.1038/nature23537