New insights into hemogenic endothelium will facilitate efforts to produce hematopoietic stem cells in vitro.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy
Nature Communications Open Access 18 January 2021
-
Cytokine-free directed differentiation of human pluripotent stem cells efficiently produces hemogenic endothelium with lymphoid potential
Stem Cell Research & Therapy Open Access 17 March 2017
-
Graphene Oxide promotes embryonic stem cell differentiation to haematopoietic lineage
Scientific Reports Open Access 20 May 2016
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Choi, K.D. et al. Cell Reports 2, 553–567 (2012).
Rafii, S. et al. Blood 121, 770–780 (2013).
Nakajima-Takagi, Y. et al. Blood 121, 447–458 (2013).
Kim, P.G. et al. Proc. Natl. Acad. Sci. USA 110, E141–E150 (2013).
Kennedy, M. et al. Cell Reports 2, 1722–1735 (2012).
Lee, D. et al. Cell Stem Cell 2, 497–507 (2008).
Medvinsky, A., Rybtsov, S. & Taoudi, S. Development 138, 1017–1031 (2011).
Antas, V.I., Al-Drees, M.A., Prudence, A.J., Sugiyama, D. & Fraser, S.T. Int. J. Biochem. Cell Biol. 45, 692–695 (2013).
Choi, E. et al. Stem Cells 30, 2297–2308 (2012).
Chen, M.J., Yokomizo, T., Zeigler, B.M., Dzierzak, E. & Speck, N.A. Nature 457, 887–891 (2009).
Lancrin, C. et al. Nature 457, 892–895 (2009).
Kaimakis, P., Crisan, M. & Dzierzak, E. Biochim. Biophys. Acta 1830, 2395–2403 (2013).
Adamo, L. et al. Nature 459, 1131–1135 (2009).
Fitch, S.R. et al. Cell Stem Cell 11, 554–566 (2012).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Sturgeon, C., Ditadi, A., Clarke, R. et al. Defining the path to hematopoietic stem cells. Nat Biotechnol 31, 416–418 (2013). https://doi.org/10.1038/nbt.2571
Published:
Issue Date:
DOI: https://doi.org/10.1038/nbt.2571
This article is cited by
-
A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy
Nature Communications (2021)
-
In vitro conversion of adult murine endothelial cells to hematopoietic stem cells
Nature Protocols (2018)
-
Cytokine-free directed differentiation of human pluripotent stem cells efficiently produces hemogenic endothelium with lymphoid potential
Stem Cell Research & Therapy (2017)
-
Conversion of adult endothelium to immunocompetent haematopoietic stem cells
Nature (2017)
-
Graphene Oxide promotes embryonic stem cell differentiation to haematopoietic lineage
Scientific Reports (2016)