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A luxRury of synthetic signals

A method for altering the substrate specificity of LuxR proteins may facilitate the engineering of artificial communication systems among cells.

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Figure 1: Engineering LuxR to respond to a new signal and not to its natural signal requires both positive and negative selection.

Bob Crimi

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Michnick, S. A luxRury of synthetic signals. Nat Biotechnol 24, 658–660 (2006). https://doi.org/10.1038/nbt0606-658

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