This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Allen, G. 1988. Biotechnology for the non-petrochemical industry. The Chemical Engineer 4:13.
Chisti, M.Y. 1988. Hydrodynamic and gas-liquid mass transfer considerations for the design of airlift bioreactors. Ph.D. Thesis, University of Waterloo, Ontario, Canada.
Chisti, M.Y. and Moo-Young, M. 1987. Airlift reactors: characteristics, applications, and design considerations. Chem. Eng. Commun. 60:195.
Chisti, M.Y. and Moo-Young, M. 1988. Hydrodynamics and oxygen transfer in pneumatic bioreactor devices. Biotechnol. Bioeng. 31:487.
Imai, Y., Takei, M., and Matsumura, M. 1987. A simple Na2SO3 feeding method for kLa measurement in large-scale fermentors. Biotechnol. Bioeng. 29:982.
Moo-Young, M., Halard, B., Alien, D.G., Burrell, R., and Kawase, Y. 1987. Oxygen transfer to mycelial fermentation broths in an airlift fermentor. Biotechnol. Bioeng. 30:746.
Graham, A.D. 1987. Design of pneumatically mixed bioreactors for the production of monoclonal antibodies. MASc Thesis, University of Waterloo, Ontario, Canada.
Ho, C.S., and Oldshue, J.Y. (eds.). Biotechnology Processes Scale-up and Mixing. American Institute of Chemical Engineers, New York, NY.
Moody, G.W., and Baker, P.B. (eds.). Bioreactors and Biotransformations, Elsevier, London. UK
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Moo-Young, M., Chisti, Y. Considerations for Designing Bioreactors for Shear–Sensitive Culture. Nat Biotechnol 6, 1291–1296 (1988). https://doi.org/10.1038/nbt1188-1291
Issue Date:
DOI: https://doi.org/10.1038/nbt1188-1291
This article is cited by
-
Modified microbial fermenter performance in animal cell culture and its implications for flexible fermenter design
Bioprocess Engineering (1994)