The Ndc80 complex links spindle microtubules to the kinetochore to ensure the proper segregation of chromosomes during mitosis. Analysis of the replication licensing factor Cdt1 during mitosis now reveals a cooperative role with the Ndc80 complex in establishing stable microtubule attachments to the spindle.
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Matson, D., Stukenberg, P. Cdt1 throws kinetochore–microtubule attachments for a loop. Nat Cell Biol 14, 561–563 (2012). https://doi.org/10.1038/ncb2513
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DOI: https://doi.org/10.1038/ncb2513