One-pot processes in which a single catalyst carries out several reactions are attractive, but typically promote the formation of by-products as well as the desired ones, and are not amenable to optimization of the individual transformations. Now, these issues have been overcome by separating the catalytic processes in time.
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Abou-Shehada, S., Williams, J. It's about time. Nature Chem 6, 12–13 (2014). https://doi.org/10.1038/nchem.1826
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DOI: https://doi.org/10.1038/nchem.1826