A new study reports a comprehensive survey of genetic diversity in natural populations of the nematode Caenorhabditis elegans. Their analyses suggest that recent chromosome-scale selective sweeps have reduced C. elegans genetic diversity worldwide and strongly structured genetic variation across its genome.
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Species richness, distribution and genetic diversity of Caenorhabditis nematodes in a remote tropical rainforest
BMC Evolutionary Biology Open Access 12 January 2013
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References
Anderson, E.C. et al. Nat. Genet. 44, 285–290 (2012).
Cutter, A.D., Dey, A. & Murray, R.L. Mol. Biol. Evol. 26, 1199–1234 (2009).
Baird, N.A. et al. PLoS ONE 3, e3376 (2008).
Anderson, J.L., Morran, L.T. & Phillips, P.C. J. Hered. 101 (suppl. 1), S62–S74 (2010).
Barton, N.H. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 355, 1553–1562 (2000).
Rockman, M.V., Skrovanek, S.S. & Kruglyak, L. Science 330, 372–376 (2010).
Gaertner, B.E. & Phillips, P.C. Genet. Res. (Camb.) 92, 331–348 (2010).
Phillips, P.C. Trends Genet. 22, 405–407 (2006).
Kiontke, K.C. et al. BMC Evol. Biol. 11, 339 (2011).
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Phillips, P. Self-fertilization sweeps up variation in the worm genome. Nat Genet 44, 237–238 (2012). https://doi.org/10.1038/ng.2201
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DOI: https://doi.org/10.1038/ng.2201
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Species richness, distribution and genetic diversity of Caenorhabditis nematodes in a remote tropical rainforest
BMC Evolutionary Biology (2013)