SNP genotyping platforms have been used to discover ∼1,000 deletion structural variants within the human genome, with median lengths ranging from 500 bp to 10.5 kb. Analyses of a subset of these provide compelling evidence of linkage disequilibrium with flanking SNPs.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Genome-wide identification of copy number variation and association with fat deposition in thin and fat-tailed sheep breeds
Scientific Reports Open Access 25 May 2022
-
A genome-wide detection of copy number variations using SNP genotyping arrays in swine
BMC Genomics Open Access 22 June 2012
-
Genomic characteristics of cattle copy number variations
BMC Genomics Open Access 23 February 2011
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Hinds, D.A. et al. Science 307, 1072–1079 (2005).
The International HapMap Consortium. Nature 437, 1299–1320 (2005).
Hinds, D.A., Kloek, A.P. & Frazer, K.A. Nat. Genet. 38, 82–85 (2006).
Conrad, D.F., Andrews, T.D., Carter, N.P., Hurles, M.E. & Pritchard, J.K. Nat. Genet. 38, 75–81 (2006).
McCarroll, S.A. et al. Nat. Genet. 38, 86–92 (2006).
Tuzun, E. et al. Nat. Genet. 37, 727–732 (2005).
Sebat, J. et al. Science 305, 525–528 (2004).
Iafrate, A.J. et al. Nat. Genet. 36, 949–951 (2004).
Sharp, A.J. et al. Am. J. Hum. Genet. 77, 78–88 (2005).
Bailey, J.A. et al. Science 297, 1003–1007 (2002).
Stankiewicz, P. et al. Cold Spring Harb. Symp. Quant. Biol. 68, 445–454 (2003).
Bhangale, T.R., Rieder, M.J., Livingston, R.J. & Nickerson, D.A. Hum. Mol. Genet. 14, 59–69 (2005).
Fredman, D. et al. Nat. Genet. 36, 861–866 (2004).
Frazer, K.A. et al. Genome Res. 13, 341–346 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Eichler, E. Widening the spectrum of human genetic variation. Nat Genet 38, 9–11 (2006). https://doi.org/10.1038/ng0106-9
Issue Date:
DOI: https://doi.org/10.1038/ng0106-9
This article is cited by
-
Genome-wide identification of copy number variation and association with fat deposition in thin and fat-tailed sheep breeds
Scientific Reports (2022)
-
Simple Sequence Repeats in the National Longitudinal Study of Adolescent Health: An Ethnically Diverse Resource for Genetic Analysis of Health and Behavior
Behavior Genetics (2014)
-
A genome-wide detection of copy number variations using SNP genotyping arrays in swine
BMC Genomics (2012)
-
Attention-Deficit/Hyperactivity Disorder Genomics: Update for Clinicians
Current Psychiatry Reports (2012)
-
Genomic characteristics of cattle copy number variations
BMC Genomics (2011)