ASC has emerged as an adaptor for inflammasome sensors in cells of the innate immune response. New inflammasome-independent roles have been identified for ASC in the control of adaptive immunity; these include the post-transcriptional regulation of cytoskeletal rearrangements.
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01 June 2012
The Nature Immunology article to which this News & Views refers has an associated addendum. We want to inform readers that some of the comments made in this News & Views, although made in good faith on the basis of the article's conclusions, may no longer be valid.
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Karakasiliotis, I., Kontoyiannis, D. ASCertaining cytoskeletal rearrangements in antigen presentation and migration. Nat Immunol 12, 923–925 (2011). https://doi.org/10.1038/ni.2114
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DOI: https://doi.org/10.1038/ni.2114
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Erratum: ASCertaining cytoskeletal rearrangements in antigen presentation and migration
Nature Immunology (2013)