Interleukin 17 (IL-17) confers protection against Trypanosoma cruzi. Surprisingly, B cells are the relevant source, producing IL-17 via a unique pathway independent of the transcription factor RORγt, induced by T. cruzi trans-sialidase.
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León, B., Lund, F. IL-17-producing B cells combat parasites. Nat Immunol 14, 419–421 (2013). https://doi.org/10.1038/ni.2593
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DOI: https://doi.org/10.1038/ni.2593
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