Lentiviral Nef protein has many functions in the evasion of host immune defenses. Another 'chink' in the host immune 'armor' has now been exposed by Nef's ability to inhibit immunoglobulin class switching.
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Peterlin, B. Nef: out and in?. Nat Immunol 7, 229–230 (2006). https://doi.org/10.1038/ni0306-229
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DOI: https://doi.org/10.1038/ni0306-229
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