Leukocytes are arrested on endothelial cells before moving through vessel intercellular junctions. The identification of another β2 integrin–dependent step may provide insights into the events and signals required for transmigration.
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Alon, R., Luscinskas, F. Crawling and INTEGRating apical cues. Nat Immunol 5, 351–353 (2004). https://doi.org/10.1038/ni0404-351
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DOI: https://doi.org/10.1038/ni0404-351