Excessive lung inflammation in response to infection or allergens can lead to tissue damage and potentially loss of organ function. The CD200-CD200R interaction acts to limit such destructive immune responses in the lung.
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Holt, P., Strickland, D. The CD200-CD200R axis in local control of lung inflammation. Nat Immunol 9, 1011–1013 (2008). https://doi.org/10.1038/ni0908-1011
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DOI: https://doi.org/10.1038/ni0908-1011
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