A new drug that activates the Wnt pathway maintains the undifferentiated state of pluripotent human and mouse embryonic stem cells. This finding opens the door to defining the precise molecular mechanism of embryonic stem cell self-renewal, which is crucial for providing a steady supply of embryonic stem cells for regenerative medicine (pages 55–63).
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Nakashima, K., Colamarino, S. & Gage, F. Embryonic stem cells: staying plastic on plastic. Nat Med 10, 23–24 (2004). https://doi.org/10.1038/nm0104-23
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DOI: https://doi.org/10.1038/nm0104-23
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