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Angiogenesis and inflammation face off

Vascular endothelial cells respond to alarm signals of the body by angiogenesis or inflammation. The balance between these two responses is now pinned to two regulators of angiogenesis. Angiopoietin-1 dampens the inflammatory response, and angiopoietin-2 boosts it (pages 235–239).

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Figure 1: Balance of powers.

Katie Ris

Figure 2: The role of angiopoietin-1 and angiopoietin-2 in inflammation and angiogenesis.

Katie Ris

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Imhof, B., Aurrand-Lions, M. Angiogenesis and inflammation face off. Nat Med 12, 171–172 (2006). https://doi.org/10.1038/nm0206-171

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