Blocking β-adrenergic receptors is a standard treatment for heart failure, but it limits the normal ability to modulate cardiac function. Targeting therapy further downstream by blocking activation of calcium-calmodulin–dependent protein kinase could provide an alternative (pages 409–407).
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Bers, D. Beyond beta blockers. Nat Med 11, 379–380 (2005). https://doi.org/10.1038/nm0405-379
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DOI: https://doi.org/10.1038/nm0405-379
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