Although attention deficit hyperactivity disorder (ADHD) is a highly heritable and common psychiatric disorder, few susceptibility genes have been identified. A new multidisciplinary genetic study in humans and mice reveals GIT1 (encoding G protein–coupled receptor kinase–interacting protein-1) as a previously undescribed ADHD susceptibility gene in humans and provides new insights into the underlying mechanisms of this condition (pages 566–572).
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Lee, YS., Silva, A. Modeling hyperactivity: of mice and men. Nat Med 17, 541–542 (2011). https://doi.org/10.1038/nm0511-541
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DOI: https://doi.org/10.1038/nm0511-541