Rosacea is a common skin disorder marked by chronic inflammation and vascular abnormalities. Two new features of the skin lesions have been identified: elevated levels of cathelicidin antimicrobial peptides and of a related serine protease. These molecules of innate immunity may represent key elements of pathogenesis, as well as new targets for effective therapies (pages 975–981).
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Bevins, C., Liu, FT. Rosacea: skin innate immunity gone awry?. Nat Med 13, 904–906 (2007). https://doi.org/10.1038/nm0807-904
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DOI: https://doi.org/10.1038/nm0807-904