Recent studies show that Musashi-2 (MSI2), a molecule that binds RNA, increases proliferation of normal and malignant blood stem cells. In humans, increased amounts of MSI2 correlate with poor prognosis of leukemia—indicating that MSI2 may be a target to treat this type of cancer.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma
Nature Communications Open Access 01 November 2017
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Nakamura, M., Okano, H., Blendy, J.A. & Montell, C. Neuron 13, 67–81 (1994).
Okano, H. et al. Exp. Cell Res. 306, 349–356 (2005).
Kharas, M.G. et al. Nat. Med. 16, 903–908 (2010).
Hope, K.J. et al. Cell Stem Cell 7, 101–113 (2010).
Ito, T. et al. Nature 466, 765–768 (2010).
Huang, T.S. et al. Stem Cells 26, 1186–1201 (2008).
Yassin, E.R. et al. PLoS ONE 4, e6719 (2009).
Wang, G.G., Pasillas, M.P. & Kamps, M.P. Mol. Cell. Biol. 26, 3902–3916 (2006).
Moore, M.A. et al. Ann. NY Acad. Sci. 1106, 114–142 (2007).
Chung, K.Y. et al. Cancer Res. 66, 11781–11791 (2006).
De Weer, A. et al. Haematologica 93, 1903–1907 (2008).
Bullinger, L. et al. N. Engl. J. Med. 350, 1605–1616 (2004).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares competing financial interests: details accompany the full-text HTML version of the paper at http://www.nature.com/naturemedicine/.
Rights and permissions
About this article
Cite this article
Moore, M. A cancer fate in the hands of a samurai. Nat Med 16, 963–965 (2010). https://doi.org/10.1038/nm0910-963
Issue Date:
DOI: https://doi.org/10.1038/nm0910-963
This article is cited by
-
Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma
Nature Communications (2017)
-
The role of nuclear pore complex in tumor microenvironment and metastasis
Cancer and Metastasis Reviews (2011)