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References
Ready, T. Nat. Med. 7, 1262 (2001).
Martin, M.J., Muotri, A., Gage, F. & Varki, A. Nat. Med. 11, 228–232 (2005).
Nguyen, D.H., Tangvoranuntakul, P. & Varki, A. J. Immunol. 175, 228–236 (2005).
Wang, L., Li, L., Menendez, P., Cerdan, C. & Bhatia, M. Blood 105, 4598–4603 (2005).
Xu, C. et al. Nat. Biotechnol. 19, 971–974 (2001).
Muller-Eberhard, H.J. Annu. Rev. Biochem. 44, 697–724 (1975).
Rao, M.S. & Civin, C.I. Stem Cells 24, 1412–1413 (2006).
Ludwig, T.E. et al. Nat. Biotechnol. 24, 185–187 (2006).
Acknowledgements
This work was supported by research grants to M.B. from the Canadian Institutes of Health Research and the National Cancer Research Institute of Canada.
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Supplementary information
Supplementary Fig. 1
Effect of heat inactivation of serum exposed to HESC lines and MEFs compared to PBS (no serum) control. (PDF 281 kb)
Supplementary Fig. 2
Binding of complement C3 from human sera to HESCs and MEFs (PDF 510 kb)
Supplementary Fig. 3
Binding of complement C3 from human serum to mixed populations of HESCs (GFP+ H9) and MEFs exposed or not to serum. (PDF 645 kb)
Supplementary Table 1
Neu5Gc content from HESC culture media and MEFs (PDF 72 kb)
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Cerdan, C., Bendall, S., Wang, L. et al. Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells. Nat Med 12, 1113–1114 (2006). https://doi.org/10.1038/nm1006-1113
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DOI: https://doi.org/10.1038/nm1006-1113
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