Molecules that regulate contraction in skeletal muscle have now found a place in the axon. In response to injury, the ryanodine receptor mediates the release of internal calcium stores, which contributes to axonal damage.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Ballentine, J.D. & Spector, M. Ann. Neurol. 2, 520–523 (1977).
Ouardouz, M. et al. Neuron 40, 53–63 (2003).
Choi, D.W. Trends Neurosci. 18, 58–60 (1995).
Medana, I.M. & Esiri, M.M. Brain 126, 515–530 (2003).
Stys, P.K., Waxman, S.G. & Ransom, B.R. J. Neurosci. 12, 430–439 (1992).
Agrawal, S.K. & Fehlings, M.G. J. Neurosci. 16, 545–552 (1996).
Teng, Y.D. & Wrathall, J.R. J. Neurosci. 17, 4359–4366 (1997).
Brown, A.M. et al. J. Neurophysiol. 85, 900–911 (2001).
Thorell, W.E., Leibrock, L.G. & Agrawal, S.K. J. Neurotrauma 19, 335–342 (2002).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wrathall, J. Muscles flex, axons die. Nat Med 9, 1347–1348 (2003). https://doi.org/10.1038/nm1103-1347
Issue Date:
DOI: https://doi.org/10.1038/nm1103-1347