A molecular pathway known for regulating cholesterol and lipid metabolism is now implicated in stroke (pages 1399–1406). The pathway is bumped up by N-methyl-D-aspartate glutamate receptors (NMDARs), which are hyperactivated in stroke and other conditions.
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Bengoechea-Alonso, M., Ericsson, J. Quelling cholesterol pathway fends off brain damage. Nat Med 15, 1358–1359 (2009). https://doi.org/10.1038/nm1209-1358
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DOI: https://doi.org/10.1038/nm1209-1358