RNA-seq is a recent and immensely popular technology for cataloging and comparing gene expression. Two papers from the international RGASP consortium report on large-scale competitions to identify the best algorithms for RNA-seq analysis, with surprising variability in the results.
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Korf, I. Genomics: the state of the art in RNA-seq analysis. Nat Methods 10, 1165–1166 (2013). https://doi.org/10.1038/nmeth.2735
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DOI: https://doi.org/10.1038/nmeth.2735