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References
Kollman, P. Chem. Rev. 93, 2395–2417 (1993).
Gilis, D. & Rooman, M. J. Mol. Biol. 272, 276–290 (1997).
Guerois, R., Nielsen, J.E. & Serrano, L. J. Mol. Biol. 320, 369–387 (2002).
Bordner, A.J. & Abagyan, R.A. Proteins 57, 400–413 (2004).
Saraboji, K. et al. Biopolymers 82, 80–92 (2006).
Ding, F. & Dokholyan, N.V. PLoS Comput. Biol. 2, e85 (2006).
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Supplementary information
Supplementary Fig. 1
Comparison of Eris ΔΔG calculations with those from other servers. (PDF 87 kb)
Supplementary Table 1
List of the Δn1 > 0 class mutants, the relative solvent accessibilities (RSA) of the mutated residues, the experimental measured ΔΔG, and the evaluated ΔΔG values by various servers. (PDF 75 kb)
Supplementary Table 2
Eris-aided structure pre-relaxation relieves backbone strains of the α-spectrin initial structure. (PDF 36 kb)
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Yin, S., Ding, F. & Dokholyan, N. Eris: an automated estimator of protein stability. Nat Methods 4, 466–467 (2007). https://doi.org/10.1038/nmeth0607-466
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DOI: https://doi.org/10.1038/nmeth0607-466
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