A wide range of methodology will be needed to bridge the gap between genome sequence and mechanistic understanding in biology. Recent advances in high-throughput genetic screening address this task.
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Collins, S., Weissman, J. & Krogan, N. From information to knowledge: new technologies for defining gene function. Nat Methods 6, 721–723 (2009). https://doi.org/10.1038/nmeth1009-721
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DOI: https://doi.org/10.1038/nmeth1009-721
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