Despite extensive study, the exact role of human anterior cingulate cortex in forming behavioral strategies is still controversial. In this issue, Williams and colleagues describe a rare opportunity to test a hypothesis about the function of this brain area in humans, by not only recording from single neurons, but also monitoring behavior immediately after surgical ablation of the area.
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Gehring, W., Taylor, S. When the going gets tough, the cingulate gets going. Nat Neurosci 7, 1285–1287 (2004). https://doi.org/10.1038/nn1204-1285
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DOI: https://doi.org/10.1038/nn1204-1285