Denali Therapeutics is taking a swing at neuroinflammation with a first-in-man trial of a RIPK1 inhibitor, while the company and others search for ways to target microglial biology more precisely.
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Mullard, A. Microglia-targeted candidates push the Alzheimer drug envelope. Nat Rev Drug Discov 17, 303–305 (2018). https://doi.org/10.1038/nrd.2018.65
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DOI: https://doi.org/10.1038/nrd.2018.65
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