The issue of propofol administration by nonanesthesiologists for upper endoscopy and colonoscopy remains controversial. A recent study investigated the efficacy and safety of a novel computer-assisted personalized sedation device. Patients sedated using the device experienced fewer serious cardiorespiratory events than patients undergoing standard sedation by bolus administration using a hand-held syringe.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Sebel, P. S. & Lowdon, J. D. Propofol: a new intravenous anesthetic. Anesthesiology 71, 260–277 (1989).
Roseveare, C. et al. Patient-controlled sedation and analgesia, using propofol and alfentanil, during colonoscopy: a prospective randomized controlled trial. Endoscopy 30, 768–773 (1998).
Heuss, L. T. et al. Patient-controlled versus nurse-administered sedation with propofol during colonoscopy. A prospective randomized trial. Am. J. Gastroenterol. 99, 511–518 (2004).
Doufas, A. G. et al. Automated responsiveness monitor to titrate propofol sedation. Anesth. Analg. 109, 778–786 (2009).
Pambianco, D. J., Vargo, J. J., Pruitt, R. E., Hardi, R. & Martin, J. F. Computer-assisted personalized sedation for upper endoscopy and colonoscopy: a comparative, multicenter randomized study. Gastrointest. Endosc. doi:10.1016/j.gie.2010.10.031.
[No authors listed] Practice guidelines for sedation and analgesia by non-anesthesiologists. Anesthesiology 96, 1004–1017 (2002).
Rex, D. K. et al. Endoscopist-directed administration of propofol: a worldwide safety experience. Gastroenterology 137, 1229–1237 (2009).
Vargo, J. J., Cohen, L. B., Rex, D. K. & Kwo, P. Y. Position Statement: Nonanesthesiologist administration of propofol for GI endoscopy. Am. J. Gastroenterol. 104, 2886–2892 (2009).
Centers for Medicaid and Medicaid Services. Revised Hospital Anesthesia Services Interpretive Guidelines. Centers for Medicare and Medicaid Services [online], (2009).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Cohen, L. Can computer-aided personalized sedation bridge troubled waters?. Nat Rev Gastroenterol Hepatol 8, 183–184 (2011). https://doi.org/10.1038/nrgastro.2011.31
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrgastro.2011.31