Irksome to debilitating, fatigue is a frequent symptom of rheumatoid arthritis (RA). Patients regard it as an important, neglected facet of the disease. An analysis of the effect of biologic therapies on fatigue has yielded disappointing results—do current treatments lack efficacy, or are we failing to measure adequate parameters?
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Acknowledgements
The authors wish to thank Dr Christina Bode of the Arthritis Center Twente at the University of Twente, the Netherlands, for substantial contributions to discussions during the preparation of this article.
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Nikolaus, S., van de Laar, M. Measuring fatigue in rheumatoid arthritis. Nat Rev Rheumatol 7, 562–564 (2011). https://doi.org/10.1038/nrrheum.2011.124
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DOI: https://doi.org/10.1038/nrrheum.2011.124