An article in The Journal of Urology addresses a frustrating feature of PSA-based prostate cancer screening, namely the fact that PSA is a fairly nonspecific marker for cancer. The authors provide a potential diagnostic test for the most common non-cancer diagnosis on prostate biopsy—asymptomatic inflammatory prostatitis (AIP)—and recommend its use as a means of avoiding unnecessary prostate biopsies.
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Murphy, A., Taylor, A. & Nadler, R. Predictive value of post-massage urine leukocyte count for AIP. Nat Rev Urol 7, 65–66 (2010). https://doi.org/10.1038/nrurol.2010.3
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DOI: https://doi.org/10.1038/nrurol.2010.3